Research use only — not for human consumption Batch 24-B released 14.07.26 · UK & EU dispatch within 24h
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Catalogue / Metabolic research / MOTS-c
MOTS-c vial, Connect Peptides
In stock UK dispatch 24h

MOTS-c

Mitochondrial-derived peptide — metabolic regulator · 2174.6 g/mol · CAS CAS 1627580-64-6
MOTS-c is a 16-amino-acid mitochondrial-derived peptide studied for its role in regulating cellular metabolism and insulin sensitivity. Third-party tested for purity and identity, each batch ships with a certificate of analysis.
99.2%
HPLC purity
2174.6
g/mol
Pass
Mass spec ID
Vial size
Also available as Prefilled pen
Open dosing calculator →

What is MOTS-c?

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is encoded within the mitochondrial genome and was first identified as a regulator of metabolic homeostasis. In research models, it is studied for AMPK pathway activation, its influence on glucose uptake and insulin sensitivity, and its behaviour as a stress-response signal communicating between mitochondria and nucleus. Ongoing research explores its relevance to metabolic ageing and exercise physiology. Each batch is independently verified for purity, identity, and endotoxin levels, with a COA provided per lot.

MOTS-c reconstitution reference

Reconstitute with bacteriostatic water. The table shows the concentration and syringe volume produced by common dilutions of a 10mg vial, for reference when preparing research stock solutions.

Bac water addedConcentration250 mcg =500 mcg =
1 ml10 mg/ml2.5 units5 units
2 ml5 mg/ml5 units10 units
3 ml3.33 mg/ml7.5 units15 units
5 ml2 mg/ml12.5 units25 units
Units measured on a standard U-100 insulin syringe (100 units = 1 ml). For other vial sizes use the peptide reconstitution calculator.

Storage & handling

Before reconstitution
Store lyophilised at −20 °C, protected from light. Stable for 24 months or longer in the sealed vial.
After reconstitution
Store at 2–8 °C and use within 28 days. Avoid repeated freeze-thaw cycles; aliquot where possible.
Specification
CASCAS 1627580-64-6
SynonymMOTS-c
Mol. weight2174.6 g/mol
Residues16 amino acids
FormLyophilised powder
SolventBacteriostatic water
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Research guides
How to reconstitute a lyophilised peptide How to store research peptides How to read a certificate of analysis Bacteriostatic water vs sterile water Are research peptides legal in the UK?
Supplied strictly as a laboratory reference material for in-vitro research. Not a medicine, food or cosmetic. Not for human or veterinary consumption, diagnostic or therapeutic use.